Behavioral disinhibition without persistent mood elevation after high dose citalopram treatment.
نویسندگان
چکیده
Dear Editor, This report suggests that emergent behavioral disinhibition during antidepressant treatment may represent milder expression of hypomania. The patient was a 33-year-old, married, Caucasian man with a 2-year history of chronic depression. He was an executive and became disabled due to depression. Laboratory work-up, including complete blood count, creatine kinase level, electrolytes, renal, liver and thyroid function tests, was unremarkable.
منابع مشابه
Two grams of sarcosine in schizophrenia – is it too much? A potential role of glutamate-serotonin interaction
Glutamate is the main excitatory neurotransmitter in the central nervous system. Dysfunction of the glutamatergic system plays an important role in the pathogenesis of schizophrenia. Therefore, glutamatergic agents such as N-methyl-D-aspartate receptor co-agonists (ie, glycine, D-cycloserine) and glycine transporter type 1 inhibitors (eg, sarcosine) are studied for their efficacy in amelioratin...
متن کاملAntidepressant drugs specifically inhibiting noradrenaline reuptake enhance recognition memory in rats.
Patients suffering from major depression often experience memory deficits even after the remission of mood symptoms, and many antidepressant drugs do not affect, or impair, memory in animals and humans. However, some antidepressant drugs, after a single dose, enhance cognition in humans (Harmer et al., 2009). To compare different classes of antidepressant drugs for their potential as memory enh...
متن کاملChronic citalopram treatment ameliorates depressive behavior associated with light at night.
Chronic exposure to light at night (LAN) is a circadian disruptor and may be linked to various health risks, including mood disorders. We recently demonstrated that chronic exposure to dim (5 lux) LAN provokes depressive-like behaviors and reduced hippocampal CA1 dendritic spine density in female hamsters. Whether this model is responsive to selective serotonin reuptake inhibitors remains unspe...
متن کاملOp-brai150136 1961..1975
Disinhibition is a cardinal feature of the behavioural variant of frontotemporal dementia, presenting as impulsive and impetuous behaviours that are often difficult to manage. The options for symptomatic treatments are limited, but a potential target for therapy is the restoration of serotonergic function, which is both deficient in behavioural variant frontotemporal dementia and closely associ...
متن کاملImproving response inhibition systems in frontotemporal dementia with citalopram
Disinhibition is a cardinal feature of the behavioural variant of frontotemporal dementia, presenting as impulsive and impetuous behaviours that are often difficult to manage. The options for symptomatic treatments are limited, but a potential target for therapy is the restoration of serotonergic function, which is both deficient in behavioural variant frontotemporal dementia and closely associ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Revista brasileira de psiquiatria
دوره 29 4 شماره
صفحات -
تاریخ انتشار 2007